静脉注射免疫球蛋白治疗

描述

免疫球蛋白医疗救助是指利用抗体的组合(正常人免疫血清球蛋白或NHIG)来治疗各种健康状况。这些疾病包括原发性免疫疾病、免疫性紫癜性出血性、慢性炎症性脱髓鞘性多发性神经病、疾病、艾滋病毒/艾滋病和莫比利病的确定病例、传染性多发性神经炎，以及一旦大量特定的免疫血清球蛋白无法获得时确定的不同感染。根据配方计算，它将通过注射到肌肉，静脉或皮下。结果持续数周。常见的关节突反应包括注射部位疼痛、肌肉疼痛和过敏反应。不同的严重关节突反应包括排泄器官问题、过敏反应、血凝块和红血球分解。对于某些类型的IgA缺乏症患者，不建议使用。在整个生理状态下使用似乎相对安全。人免疫血清球蛋白是从人血浆中产生的。它含有抗几种病毒的抗体。 Immunoglobulin medical aid is employed during a type of conditions, several of that involve cut or abolished protein production capabilities, that vary from a whole absence of multiple varieties of antibodies, to IgG taxonomic group deficiencies (usually involving IgG2 or IgG3), to different disorders during which antibodies square measure at intervals a traditional quantitative vary, however lacking in quality-unable to retort to Antigens as they ordinarily ought to–leading to an exaggerated rate or exaggerated severity of infections. In these things, immune serum globulin infusions confer nonviolence to infection on their recipients by increasing the quantity/quality of IgG they possess. Immune serum globulin medical aid is additionally used for variety of different conditions, as well as in several response disorders like myositis in a trial to decrease the severity of symptoms. Immune serum globulin medical aid is additionally employed in some treatment protocols for secondary immunodeficiencies like human immunological disorder virus (HIV), some response disorders (such as immune blood disease and Kawasaki disease), some medical specialty diseases (multifocal motor pathology, stiff person syndrome, degenerative disorder and myasthenia gravis) some acute infections and a few complications of organ transplantation. Immunoglobulin medical aid is very helpful in some acute infection cases like medical specialty HIV infection and is additionally thought of the quality of treatment for a few response disorders like Guillain–Barré syndrome. The high demand that including the issue of manufacturing immune serum globulin in giant quantities has resulted in increasing international shortages, usage limitations and assignation of immune serum globulin. Different national bodies and medical associations have established variable standards for the utilization of immune serum globulin medical aid. Although immune serum globulin is usually used for long periods of your time and is mostly thought of safe, immune serum globulin medical aid will have severe adverse effects, each localized and general. Hypodermic administration of immune serum globulin is related to a lower risk of each general and localized risk when put next to blood vessel administration (hyaluronidase-assisted hypodermic administration is related to a bigger frequency of adverse effects than ancient hypodermic administration however still a lower frequency of adverse effects when put next to blood vessel administration). Patients UN agency square measure receiving immune serum globulin and knowledge adverse events square measure generally suggested to require anodyne and antihistamine before their infusions to scale back the speed of adverse effects. Further premedication is also needed in some instances (especially once initial obtaining at home with a replacement dosage), Orasone or another oral steroid.