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抗菌和抗真菌的功效玫瑰花瓣(Rosa籼稻)提取物对口腔微生物-体外研究

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简介:大自然所赋予许多草本植物被发现有杀菌和抑菌作用,这些已经被使用。其中一个到处都是玫瑰容易与其他草药。人体的许多疾病的细菌和真菌感染。尤其是在口腔免疫受损患者影响真菌和细菌感染。使用这些合成药物可能导致的副作用和抗生素耐药性。因此,目前的研究都是关于确定玫瑰的抗菌和抗真菌作用。因此,决定在牙科中的应用,这些可以作为一个替代合成药物来治疗疾病。材料和方法:罗莎籼稻的花瓣被用于ethanolic提取物的制备。100克的粉样品浸泡在300毫升乙醇索氏仪器。样品经索氏仪器被溶解在DMSO(二甲亚砜)。 This is used to detect Antimicrobial activity of Rosa indica. Both zone of inhibition and minimum inhibitory concentration (MIC) were evaluated using Agar well diffusion method and micro-dilution method respectively. The results thus obtained were then compared with the control against Streptococcus mutans and Candida albicans. Results: Zone of inhibition of rose extract was found to be 18 mm, 16 mm, 10 mm at 1000 μg, 500 μg, 250 μg against Streptococcus mutans, which was less than the control kanamycin (24 mm) and zone of inhibition was 26 mm, 24 mm, 22 mm at 1000 μg, 500 μg, 250 μg against Candida albicans which was greater than the control ketaconozole (19 mm). Thus, the rose extract has both antibacterial and antifungal property. Antifungal effect is more than antibacterial effect of rose. Discussion: Zone of inhibition of rose extract is more when compared to ketaconozole, an antifungal drug and less than kanamycin, an antifungal drug. Rose extract has both antibacterial and antifungal property. Antifungal effect of rose is more than antibacterial effect and it is very effective against fungal diseases. Conclusion: We can state that roses have both antibacterial and antifungal activity. In the present study rose extract has more antifungal property than antibacterial property. With this finding, rose can be used as a potent antifungal drug to treat fungal infections.

Swetha R, Shobana R, Sunayana M, Prabu D, Raj Mohan Naveen统治

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