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COPD 2018:神经肌肉电神经刺激对中重度慢性阻塞性肺疾病患者的影响——一项试点研究

摘要

神经肌肉电神经刺激(NMES)是一种正在研究的新方式，因为它与慢性阻塞性肺疾病(COPD)患者的股四头肌力量和步行距离有关。这项小型试点研究的目的是观察和吸收尽可能多的关于方法和学习结果的信息。来自这项小型试点研究的信息将为关于这种新模式的更大的全国性研究的可能性提出建议。为此目的，人们认为采用混合方法是适当的。本次可行性研究共纳入7例中重度COPD患者，其中实验组4例，对照组3例。在患者同意后，完成了股四头肌力量测试和6分钟步行测试(6MWT)。客观测量在本研究的基线，即第4周和第8周进行。所有受试者都报告了积极的结果，其中实验组受益最大。然而，由于总体抽样较少，结果并不显著。为了更好地了解患者在NMES期间的感受，在研究结束时向实验组分发了一份自行设计的问卷。 Constant feedback was kept during the study duration between the researcher, intermediary physiotherapist and the subjects. Constant feedback and the results from the questionnaire were important for the researcher to present recommendations based on the strength, limitations and learning outcomes. This feasibility study provided guidance for larger more randomized national studies to maximize the benefits of NMES in COPD patients. Recent Publications 1. Madocks M, Nolan C, Man W, Polkey M, Hart N, et al. (2016) Neuromuscular electrical stimulation to improve exercise capacity in patients with severe COPD: a randomised double-blind, placebo-controlled trial. The Lancet Respiratory Medicine 4(1):27???36. 2. Kharbanda, Krishnan S and Ramakrishna A (2015) Prevalence of quadriceps muscle weakness in patients with COPD and its association with disease severity. International Journal of Chronic Obstructive Pulmonary Disease 1727. 3. Giavedoni S, Deans A, Mccaughtey P, Drost E, Macnee W, et al. (2012) Neuromuscular electrical stimulation prevents muscle function deterioration in exacerbated COPD: A pilot study. Respiratory Medicine 106(10):1429???1434. 4. Abdellaoui A, Prefaut C, Gouzi F, Couillard A, Coisy-Quivy M, et al. (2011) Skeletal muscle effects of electrostimulation after COPD exacerbation: a pilot study. European Respiratory Journal 38(4):781???788. 5. Maffiuletti N (2010) Physiological and methodological considerations for the use of neuromuscular electrical stimulation. European Journal of Applied Physiology 110(2):223???234. Attending this conference is a professionally rewarding experience. In addition to socializing with colleagues from other institutions and a trip to a possibly exotic locale, the two main reasons to attend conference are to hear presentations and to converse with other researchers. Listening to presentations will inform you of what others are doing will inspire research ideas of your own, and will expose you to different styles of presentation. Randall Debattista

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