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慢性阻塞性肺病2018:尼日利亚北部卫生环境中艾滋病毒阳性青少年中的结核病感染和相关复杂情况- ginika egesimba热带医学研究所

摘要

背景:青春期是生理、心理、教育、疾病和其他生活经历的过渡时期。感染艾滋病毒使他们非常容易感染结核病。这一跨越一系列生活环境的过渡年龄与疾病治愈的复杂性有关，特别是与艾滋病毒合并感染的结核病。本文研究了10-19岁PLHIV青少年结核病流行的意义和相关的复杂性。方法:对2014年10月1日至2015年12月31日使用Pro-ACT MSH数据库收集的15个月的数据进行横断面回顾性分析，并使用Excel进行分析。分析的数据是从41个受支持的综合卫生机构收集的每月常规数据。结果:787例(M-357;F-430)对青春期PLHIV进行了结核病筛查，其中32人(M-16;F-16)进一步评估假定结核病例是否为结核。20 (M-8; F-12) of them were diagnosed with TB while 15 (M-6; F-9) were commenced on treatment accounting for a 2.5% TB prevalence over the period. In categorizing these adolescents into 10-14 and 15-19 age group, the 10-14 years age group had the highest number of HIV infection and invariable presented more number of adolescents to be screened for TB (416 vs 371). TB preponderance was reported within 15-19 years, females carried more of the burden and more of missed treatment is reported in older adolescent. (4 TB cases for the ages of 15-19 as against 1 for age 10-14). Conclusions: The highly mobile nature of older adolescent (15-19) may account for preponderance of TB cases in the group. With more presumptive TB cases identified among younger adolescent (10-14), active follow up is required as they transition to the mobile age which are more prone to TB This finding provides opportunity to explore further why older adolescent both carry TB burden. among PLHIV as well as missed treatment opportunitie Tuberculosis (TB) is caused by bacteria belonging to the Mycobacterium tuberculosis complex. About a third of the world's population is latently infected with the TB bacteria. HIV infection leads to immune deterioration, thus providing a platform for the activation of latently infected tuberculosis. Tuberculosis is the leading cause of death among people infected with HIV in resource-limited countries. About a third of people infected with HIV are co-infected with TB, most of them living in low- and middle-income countries. Up to 11% of newly detected TB cases are infected with HIV and up to 23% of newly detected HIV cases are co-infected with TB. A high prevalence of HIV / TB co-infection is described elsewhere. Estimating the extent of pulmonary tuberculosis (TB) and the factors associated with it in people infected with HIV can be useful at the political level as well as for the management of each patient for best results. In resource-constrained countries, HIV is often diagnosed at an advanced stage of the disease and in association with other comorbidities related to the deterioration of the immune system Ginika Egesimba

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