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开发和评估的抗氧化,抗癌活性Poly-Herbal组合

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肺癌的发生和相关死亡是逐年上升。这是在全世界女性癌症死亡的首要原因。因此,需要找到另一种治疗肺癌的治疗和管理以最小的副作用。目前的研究工作的目标是发展poly-herbal胶囊的配方组成hydro-alcoholic(20:80)提取使用罗勒属圣所,姜黄,兰,Teriminalia bellerica, Teriminalia chebula, Piper longum, Piper初步和生姜肺癌疾病的管理。这poly-herbal胶囊配方有潜在的抗氧化和抗癌生物活性分子。poly-herbal胶囊配方是制定和标准化的按质量标准化的指导方针。优化poly-herbal胶囊配方被使用标准评价胶囊制剂的评价参数。抗氧化和抗癌活性测定采用DPPH (2, 2-diphenyl-1-picrylhydrazyl)和铁离子还原能力测定(压裂)和(MTT) 3 - (4 5-dimethylthiazol-2-yl) 2, 5-diphenyl溴化四唑对A549肺癌细胞系。制药参数即重量差异的评价结果;和水分分析被发现在官方限制。 The dissolution studies represented that drug release of maximum up to 98.67% at 30 minutes. The DPPH assay and FRAC assay activity of the poly-herbal extract is found to potent as similar standard drug. The optimized finished poly-herbal formulation showed significant cytotoxic activity against A549 lung cancer cell line. The results of all emulation parameters revealed that it could be used for the treatment and management of lung cancer disease.

罗伯托Kumar Mahto Ajay Kumar Shukla说

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