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不会影响Narcuss tazetta提取物对蚕豆根尖种子和在某些器官在老鼠身上

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在本研究评估基因毒性和细胞毒性的影响原油水提取物的Narcuss tazetta l .蚕豆根尖种子后存储,3和6个月。在第一个实验中,Narcuss tazetta提取造成损失的细胞有丝分裂指数伴随着相当大比例的染色体畸变。这些异常包括粘性、干扰染色体、桥梁、落后染色体和微核。抑制萌发的比例达到26.37%,此前存储6个月但达到63.33%后存储为一个月。值7.44%最低记录细胞有丝分裂指数极高narcuss提取物治疗,疗程1个月。六个月的有丝分裂抑制是低于1和3个月。限制有丝分裂抑制的程度达到23.14%,14.36%和13.45%后narcuss提取和存储,处理3和6个月。在第二个实验中,提取的细胞遗传学效应Narcuss tazetta残留在蚕豆根尖种子储存6个月后评价Siwiss老鼠。这些研究包括骨髓染色体畸变分析、脾细胞和精母细胞。结果表明,在不同的小鼠组织诱导的细胞遗传学效应提取Narcuss tazetta残留物和喂养时间的增加而增加。喂养小鼠蚕豆根尖的种子存储6个月染色体畸变的诱导有显著的影响。 The percentage of chromosome aberrations reached 10.4±0.84, 11.4±0.77 and 10.2±0.70 (P<0.01) in bone marrow, spleen and spermocytes cells respectively after feeding mice for three months. the abnormalities in spermatocytes was significant increase in univalent formation only,predominantly of the sex chromosomes.The obtained results indicate that extracts Narcuss tazetta residues in stored Vicia faba seeds have potential geneotoxic effect in mice under the conditions tested. These results indicated that the narcuss extracts had a genotoxic effects on germination, mitotic division in plant and bone marrow, spleen and spermatocytes cells in mice.

法丽雅。穆罕默德,柴那m . El-Ashry Kowser m . El - Sherbeny Aziza A.Ibrahem

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