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临床样品中皮癣菌的优化分离及体外药敏试验

摘要

印度是一个巨大的次大陆，地形非常多样，位于世界的热带和亚热带地带。在研究中，由皮肤科医生对足癣感染患者进行临床检查。按标准程序进行分离和验证试验，采用圆盘扩散法进行抗真菌药敏试验。其他情况，如脂溢性皮炎、牛皮癣、斑秃、毛囊炎和假性包皮，可能与头癣和其他癣相似，必须加以识别。本文对66例皮肤癣患者进行了研究。男性为51例(77%)，女性为15例(23%)。男女比例为3.4:1。最常见的年龄组为21-30岁，有20例(23%)。最不常见的年龄组为61-70岁，3例(4%)。体癣以21 ~ 30岁年龄组多见，13例(37.14%)，男性29例(82.85%)，女性6例(17.15%)。甲癣以31 ~ 40岁年龄组的6例(37.5%)多见，男性10例(62.5%)多于女性6例(37.5%)。头癣多见于51 ~ 60岁年龄组2例(40%)，男性多见于5例(100%)。In tinea pedis, one case was seen in the age group of 11-20 years and the other in the age group of 41-50 and 51-60 years, and was more common in males with 3 cases (100%).Tinea barbae was more common in the age group 21-30 years with 2 cases (66.66%) .Tinea capitis was more common in the age group of 31-40 years with 2 cases (66.66%) and was more common in females with 3 cases (100%). Tinea manuum was more common in the age group of 31-40 years and in males with 1 case (100%). In males, commonest infection was T. corporis while in female commonest infection was T.corporis.rate of direct microscopy and culture (78.79%). About 89.47% of the dermatophytes grew faster in DTM with compare to SDA, so the growth rate of dermatophyte is better in DTM. A total of thirty five species of dermatophytes were isolated and identified. T.rubrum 15(42.85%) is commonest among other isolates.Ketoconazole showed best susceptibility i.e 26 (74.28%). The present study suggests that every patient of tinea infection should be properly studied for mycological examination and should be treated accordingly. This study revealed that Ketaconazole highest susceptibility.DTM is better medium than SDA.

Amodkumar Yadav, AD Urhekar, Vijay Mane, Mahesh Singh Danu, Nitin Goel和Ajit KG

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