编辑雷竞技app下载苹果版

MedChem & cadd - 2013:植物化学的成分来自金合欢nilotica Delile激酶抑制活动-奥古斯汀a Ahmadu尼日尔三角洲大学

文摘

茎皮的金合欢nilotica Delile (L),两个新的peltogynoids, acanilol(1)和acanilo B(2)分离与已知的三萜烯羽扇烯酮。新化合物的结构的基础上,建立了它们的光谱数据,主要是紫外线、核磁共振和质谱分析。新化合物检测激酶抑制剂对CDK1 GSK3,对照和DYRK1A acanilol B被认定为DYRK1A抑制剂,19µm的IC50。19种不同的金合欢在美洲包含生氰苷,如果暴露于一个专门划分苷的酶,可以释放氰化氢(HCN)“叶子”。这有时会导致有毒的死牛。一个有趣的事实是,当他们放牧例如长颈鹿,一些洋槐释放毒素称为丹宁酸。这使得树叶不能食用,导致动物寻求“绿色牧场”。毒素可以是非常危险的动物如果吞下,可以是致命的。医学,相思是口服高胆固醇,糖尿病,肠易激综合症(IBS)和肥胖。渗出物口香糖从这棵树被称为阿拉伯树胶和收集自法老时代制造的药物、染料和颜料。 It is also used to remove toxins from the body and as a prebiotic to promote "good" bacteria in the gut. Acacia is applied to the skin inside the mouth for inflammation of the plaque and gums (gingivitis). Part of the symbolism of acacia therefore includes resurrection, immortality, secret love, affection, friendship, elegance, renewal, courage, purity, etc. The black wood acacia (Acacia melanoxylon), a fast growing tree that grows in USDA zones 9 to 11 have roots so aggressive that they easily damage the sidewalks and foundations of buildings in addition to invading the spaces of other plants. The acacia provides shelter (ants live inside the thorns) and food (they eat nectar). In return, the ants protect the plant from the herbivores. The acacia develops pea-shaped flowers composed of 5 petals. Acacia fiber is also said to be prebiotic (a non-digestible dietary ingredient in dietary fiber that can stimulate the growth of beneficial bacteria in the intestines). Vachellia nilotica is a 5–20 m tall tree with a dense spherical crown, stems and branches usually dark to black in color, cracked bark, grayish-pink bar, and exuding poor reddish gum. The tree has fine, straight, clear and gray spines in axillary pairs, usually in 3 to 12 pairs, 5 to 7.5 cm (3 in) long in young trees, mature trees generally without thorns. The leaves are bipinnate, with 3–6 pairs of pinnules and 10–30 pairs of leaflets each, tomentose, rachis with a gland at the bottom of the last pair of pinnules. Flowers with globular heads, 1.2–1.5 cm in diameter, of shiny golden yellow color, arranged either axillary or whorls on peduncles 2–3 cm long situated at the end of the branches. The pods are strongly tightened, hairy, white-gray, thick and gently tomentose. Its seeds number around 8000 / kg. It has largely naturalized outside its original range, notably in Zanzibar and Australia. Acacia gum is widely used as a food additive. In addition, as acacia fiber ferments slowly, it can reduce the side effects of fermentation. The production of intestinal gas resulting from fermentation can induce abdominal symptoms. The species name nilotica was given by Linnaeus from the best known range of this tree along the Nile. The V. nilotica plant then became in turn the type species of the Linnean genus Acacia (which do not all have thorns, even if they bear their name). For the current reclassification of this species and other species historically classified in the genus Acacia, see Acacia. Due to its high soluble fiber content, acacia fiber is said to help lower cholesterol, control blood sugar, protect against diabetes, and help treat digestive disorders such as irritable bowel syndrome. (IBS). When taken orally: Acacia is probably safe for most adults in amounts generally found in food. When taken orally in medicinal amounts, acacia is safe up to 30 grams per day has been used safely for 6 weeks. However, it can cause minor side effects, including gas, bloating, nausea, and loose stools.

奥古斯汀a Ahmadu

阅读全文下载全文