研究和评论:材料科学杂雷竞技苹果下载志》上
菜单ISSN: 2321 - 6212
ISSN: 2321 - 6212
Ceren Peksen, Remzi Caylak, Nusret高丝和艾丁•道昂
Turkiye私人Ortopedia Ondokuz马邑村大学医院,Turkiye Osmangazi大学Turkiye安纳托里亚大学Turkiye
ScientificTracks抽象:启J垫。Sci >
DOI:10.4172 / 2321 - 6212 c1 - 014
长期生存和有利的结果骨科植入物的使用是由骨植入植入物附近的骨整合和没有感染。增强抵抗殖民,植入材料可能与抗菌改性涂料。银离子的抗菌作用机制与硫醇组织相互作用密切相关。在这项研究中,基于Ag) +离子掺杂磷酸氢钙陶瓷技术涂层Ti6AlV植入物进行评估,防止implant-related感染通过比较羟磷灰石(HA)涂层和不加涂层的钛植入体内。Ag) +离子掺杂磷酸氢钙粉体沉积基于Ti6Al4V植入用elestrospray沉积技术。高真空下喷雾涂层样品烧结RF(射频)。烧结过程后表面形态的植入物和扫描电子显微镜观察。在手术之前,兔子随机获得涂层植入或裸露的植入物。第一组的植入物被涂上一层Ag) +离子掺杂纳米大小磷酸钙陶瓷粉为基础。第二组的移植与羟基磷灰石(HA)涂层,剩下的植入物(组3)使用没有任何涂层。 Implants were inserted left femurs of animals from knee regions with retrograde fashion. Before implantation of implants 50 µl solution containing 106 CFU/ml methicillin reistance Staphylococcus aureus (MRSA) injected intramedullary canal. Rabbits were monitored for 10 weeks. At the end of the 10 weeks animals were sacrificed and rods were extracted in a sterile fashion. Swab cultures were taken from intramedullary canal. Bacteria on titanium rods were counted. Histopathological evaluation of bone surrounding implants was also performed. In conclusion, Ag+ ion doped calcium phosphate based ceramic nano powder coated Ti6Al4V implants may prevents bacterial colonisation and infection compared with those for implants without coating and HA coated implants. Recent Publications: 1. Kose N, Otuzbir A, Peksen C, Kirmitçi A, Dogan A (2013) A silver ion-doped calcium phosphate-based ceramic nanopowder coated prosthesis increased infection resistance, Clinical Ortopaedics and Related Research, 8:25322539. 2. Kose N, Caylak R, Peksen C, Kiremitci A, Burukoglu D, Koparal S, Dogan A (2016), Silver ion doped ceramic nanopowder coated nails prevent infection in open fractures: in vivo study, Injury, 47:320-324. 3. Bostancıoglu B, Peksen C, Genc H, Gurbuz M, Karel F, Koparal S, Kose N, Dogan A, Koparal A (2015), Amnalyses of the modulatory effects of antibacterial silver doped calcium phosphate based ceramic nano-powder on proliferation, survival ande agiogenic capacity of different mammalian cells in vitro, Biomedical Materials, 10: 045024. 4. Yang, CY et al. (1997) In vitro and in vivo mechanical evaluations of plasma‐sprayed hydroxyapatite coatings on titanium implants: The effect of coating characteristics, Journal of Biomedical Materials Research Part A, 37: 335-345. 5. Zhao, L et al. (2009) Antibacterial coatings on titanium implants, Journal of Biomedical Materials Research Part B: Applied Biomaterials 91: 470-480.
Ceren Peksen陶瓷工程专业学位Dumlupinar大学理学硕士和博士学位从安纳托里亚大学陶瓷工程科学研究所Turkiye,分别在2006年和2012年。2014年,她加入了陶瓷和玻璃,Ondokuz马邑村大学作为一个讲师,成为助理教授。她目前的研究兴趣包括陶瓷粉合成、陶瓷表面涂层、生物陶瓷、抗菌材料和材料特性。
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